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Business hotels in St. Louis

Welcome to the wonderful city of St. Louis, Missouri, located right in the heart of the United States. Known for its iconic Gateway Arch and rich history, St. Louis is a vibrant destination that combines midwestern charm with a cosmopolitan vibe. This city provides an ideal environment for business travelers, with its robust economy, exciting attractions, and a wide array of business hotels for the discerning traveler.
St. Louis is not just a bustling business hub, but a city of culture and heritage. It’s home to the stunning Cathedral Basilica of St. Louis with its intricate mosaics, a testament to the city’s deep-rooted Catholic tradition. Right after your meeting, you can also immerse yourself in fine arts at the St. Louis Art Museum or enjoy a classical concert at the Powell Symphony Hall, both within easy reach of most business hotels.
No trip to St. Louis would be complete without an outing at Forest Park. Apart from being the backdrop to the 1904 World’s Fair, it's now an oasis in the city with museums, a zoological park, and beautifully manicured lawns - perfect for unwinding after a day of business meetings. As the sun sets, the Delmar Loop, a six-block entertainment and shopping district, beckons. Experience St. Louis nightlife with its array of eateries, shopping spots, and vibrant live music venues.
Whether your day in St. Louis is packed with meetings or you have some time to explore, you can find comfort and convenience in the range of business hotels scattered across the city. These establishments cater to varying needs, from luxury accommodations with meeting rooms and high-speed internet to cozier establishments that provide a home-away-from-home atmosphere. Discover St. Louis, Missouri - the perfect fusion of business and leisure, industry and culture, within the United States.

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10 properties available

  • Hyatt Regency St. Louis at The Arch
    Hyatt Regency St. Louis at The Arch
    315 Chestnut St, St. Louis, US
    • Free WiFi
    • Fitness facilities

    An upscale lodging with beautiful city views. Providing classy suites, outdoor pool, and a fitness center for a delightful stay.

    Good

    3,386 reviews

    4.2
    From$198.44per room / per night
    Choose room
  • Moonrise Hotel
    Moonrise Hotel
    6177 Delmar Blvd, St. Louis, US
    • Free WiFi
    • Fitness facilities

    Indulge in excellent service and state-of-the-art facilities. Boasting a desirable location, ideal for business travelers, with modern amenities for a regal experience.

    Good

    1,502 reviews

    4.5
    From$190.96per room / per night
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  • Hotel Saint Louis, Autograph Collection
    Hotel Saint Louis, Autograph Collection
    705 Olive Street, St. Louis, US
    • Free WiFi
    • Fitness facilities

    Experience luxury with a personal touch. With elegant rooms, great facilities, and a prime location, this property promises a memorable stay.

    Good

    390 reviews

    4.4
    From$207.69per room / per night
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  • Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
    Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
    3550 Samuel Sheppard Drive, St. Louis, US
    • Free WiFi
    • Fitness facilities

    This vibrant hotel offers a unique blend of art and hospitality. Features modern, stylish rooms and excellent amenities for a delightful stay.

    Good

    950 reviews

    4.3
    From$178.81per room / per night
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  • Four Seasons Hotel St Louis
    Four Seasons Hotel St Louis
    999 North Second Street, St. Louis, US
    • Fitness facilities

    Splendid and upscale, boasts contemporary rooms and luxurious amenities. Comes with a relaxing spa and an incredible rooftop pool.

    Excellent

    981 reviews

    4.7
    From$458.78per room / per night
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  • The Last Hotel
    The Last Hotel
    1501 Washington Ave, St. Louis, US
    • Free WiFi
    • Fitness facilities

    Boasts of contemporary design and unbeatable service. Savour fine dining at onsite restaurant and unwind at the rooftop bar with splendid city views.

    Average

    1,079 reviews

    3.8
    FromRead more info about this hotelper room / per night
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  • Live by Loews - St.Louis
    Live by Loews - St.Louis
    799 Clark ave, St. Louis, US
    • Free WiFi
    • Fitness facilities

    High-end hotel provides a luxurious experience with top-notch amenities. Features conference rooms, gym, and high-speed Wi-Fi.

    Good

    913 reviews

    4.5
    From$251.12per room / per night
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  • The Westin St. Louis
    The Westin St. Louis
    811 Spruce St, St. Louis, US

    Known for its modern designs and comfortable settings. Will make your stay memorable with excellent amenities, including a heart-melting swimming pool.

    Good

    945 reviews

    4.2
    From$217.89per room / per night
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  • The Royal Sonesta Chase Park Plaza St. Louis
    The Royal Sonesta Chase Park Plaza St. Louis
    212 N Kingshighway, St. Louis, US
    • Free WiFi
    • Fitness facilities

    A luxurious stay with exceptional amenities. Boasting a spectacular pool and convenient location to business hubs. A highlight of your trip.

    Good

    950 reviews

    4.4
    From$249.71per room / per night
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  • Marriott St. Louis Grand
    Marriott St. Louis Grand
    800 Washington Ave, St. Louis, US
    • Free WiFi

    Boasting luxurious rooms and top-notch amenities, this hotel is an excellent choice. Enjoy modern facilities such as a fitness center and a renowned restaurant.

    Average

    959 reviews

    4
    From$188.04per room / per night
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Business-Friendly Dining and Cafés in St. Louis Missouri

  1. Free stock photo of food restaurant, vintage, vintage restaurant
    St. Louis

    Truffles Restaurant

    Truffles Restaurant in St. Louis offers an upscale dining experience perfect for business dinners. They offer a wide variety of gourmet dishes in an elegant environment, making it an excellent place for business discussions over a meal.

    1
  2. A stylish coffee shop interior in Yokosuka, Japan with modern decor and coffee brewing equipment.
    St. Louis

    Café Osage

    Café Osage, located within the Bowood Farms complex, is a delightful café that serves local, home-grown produce. Its relaxing setting offers a perfect escape from the hustle and bustle of business activities.

    2
  3. St. Louis

    Cunetto House of Pasta

    Cunetto House of Pasta, on 'The Hill', is an ideal location for business gathering. Known for its hearty Italian dishes and wine selection, it provides a comfortable ambiance for casual business talks.

    3
  4. Enjoy a luxurious rooftop poolside lounge with beautiful sunset views.
    St. Louis

    Three Sixty

    Three Sixty, a rooftop bar with a panoramic view of downtown St. Louis, offers a unique spot for after-work business drinks. It offers a diverse menu as well as outdoor seating areas making it a great place to connect with colleagues or clients.

    4
  5. Cozy outdoor seating at a Parisian café with festive decorations.
    St. Louis

    Brasserie by Niche

    Brasserie by Niche, a classic French bistro, serves timeless French cuisine. With its cozy environment and excellent service, it's an ideal place for an intimate business lunch or dinner.

    5

Business centers in St. Louis Missouri

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    St. Louis

    Cortex Innovation Community

    The Cortex Innovation Community, located in mid-town St. Louis, is a thriving hub of business and technology. It hosts a growing innovation ecosystem of tech startups, established companies, and pioneering educational institutions.

    1
  2. Free stock photo of adult, baku, beach
    St. Louis

    T-Rex

    The T-Rex Building is a co-working space and business incubator in downtown St. Louis that houses dozens of startups and small businesses. It provides entrepreneurs with the resources they need to build and grow their businesses.

    2
  3. Close-up view of a spiral stone staircase showcasing intricate geometric patterns.
    St. Louis

    Helix Center

    Helix Center Biotech Incubator is a high-tech bio-science startup incubator located in St. Louis county. It offers lab space and office space, as well as support services to help businesses in their early stages.

    3
  4. Iconic Gateway Arch in St. Louis captured against a clear blue sky.
    St. Louis

    CIC St. Louis

    Cambridge Innovation Center (CIC) in St. Louis provides co-working spaces, offices, and labs for startups, growth companies, and established enterprises in multiple sectors. It aims to attract innovative companies from all over the globe.

    4
  5. Professional businesswoman explaining budget strategy on a whiteboard during a meeting.
    St. Louis

    OPO Startups

    The OPO Startups is a co-working center located in the historic Post Office building in downtown St. Charles. It provides weekly events, workspace, conference rooms, and accelerator programs for startups and freelancers.

    5

Conference Centers & Event Venues in St. Louis Missouri

  1. Inside Curitiba's sleek bus station, capturing urban transit architecture in a bustling Brazilian city.
    St. Louis

    America's Center Convention Complex

    Located in the heart of downtown St. Louis, the America's Center offers expansive and versatile spaces perfect for conferences, conventions, and commercial events. Boasting a total of 502,000 square feet of exhibit space and 80 meeting rooms, it can accommodate events of virtually all sizes.

    1
  2. Historic 1830 Station building with modern skyscrapers in the background.
    St. Louis

    St. Louis Union Station

    St. Louis Union Station, a historical landmark transformed into a modern event venue, offers a blend of old world charm and contemporary design. The Grand Hall, with its sweeping archways, fresco and gold leaf detailing, mosaics and art glass windows, can host up to 500 people.

    2
  3. A blurred figure views artwork in a London museum, emphasizing artistic interpretation.
    St. Louis

    City Museum

    The City Museum is an entertaining mix of children's playground, fun house, and architectural marvel made out of unique, found objects. The 600,000 square-foot museum can be hired for private events and offers a breathtaking backdrop for both formal and casual gatherings.

    3
  4. A surreal scene with a silhouetted man approaching a bright arched doorway in a dark room.
    St. Louis

    The Gateway Arch

    Thrill your guests with a celebration at 'The Gateway Arch', an international symbol of St. Louis with panoramic views of the city. The sleek, stylish and contemporary design of the venue coupled with its iconic architecture makes it a unique location for hosting memorable events.

    4
  5. Discover serenity in a beautifully manicured garden with a central fountain, offering a peaceful retreat in the UK.
    St. Louis

    Chase Park Plaza

    The Chase Park Plaza Royal Sonesta Hotel is a vibrant gateway to the city’s arts and entertainment district. With luxury accommodations and versatile event spaces, this venue is perfect for conferences, gala dinners or intimate celebrations, projecting an ambiance of historic elegance with contemporary comforts.

    5

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